Six top firms held more than $1 billion in equity: Arch Venture Partners, Novo Holdings, Flagship Pioneering, RA Capital Management, Perceptive Advisors, and SoftBank. Asia Pacific ; Grow your revenue with all-in-one prospecting solutions powered by the leader in private-company data. Our research shows that VC companies invested in 2,200 biotech start-ups worldwide in 2016; by 2021, that number had grown to 3,100. Our Standards: The Thomson Reuters Trust Principles. Find the right companies, identify the right contacts, and connect with decision-makers with an all-in-one prospecting solution. But two of those investment firms have emerged as major leaders, not only in the number of biotech funding rounds led, but also in overall dollars invested into the industry. Additionally, Bain Capital Crypto closed a $500 million fund in March 2022, and the firm announced a $2.4 billion Tech Opportunities fund earlier this month. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! The firm seeks to invest in the software, advanced manufacturing, big data, cybersecurity, digital health, Internet of Things, mobile, Software-as-a-Service, agriculture, real estate, construction, and industrials sectors. Apeiron, Christian Angermayer's investment firm, is based in Malta and has $3.5 billion in assets under management. Largest investment: 26.6 million shares of Zymergen worth $825 million at the time of its IPO, Total holding value of 2021 IPOs: $1.1 billion. WebThe lifeblood of revolutionary medical technologies is venture funding. This fact is the cornerstone of the firms infrastructural drive in the biological sciences, healthcare, and Biotech company sectors. The firm seeks to make minority investments in seed-stage, early-stage, and later-stage companies. , which conducts research and development of pharmaceuticals related to COVID-19. The biotech market has set a record for the number of initial public offerings in 2021. Flagship CEO Noubar Afeyan previously told Insider about the four-step creation process behind the firm's companies. 7 On May 29, partners submitted a Form D stating their intent to raise a $380 million sixth fund, to be named MPM BioVentures 2014. WebThe 45 most important VCs in Texas, according to other VCs. After all, you cannot rush your way into building long-term relationships! WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! Largest investment: 9.6 million shares of Erasca worth $153 million at the time of its IPO, Total holding value of 2021 IPOs: $539.4 million. WebThe 45 most important VCs in Texas, according to other VCs. The firm invests in disruptive and emerging B2B software, APIs, applications, frontier tech and marketplaces across a number of industries including supply chain, FinTech and workforce efficiency. 9 See announcement on the firms blog, http://indexventures.com/news-room/blog/our-new-fund-for-building-iconic-businesses Founded in 2006, Breyer Capital is a venture capital firm headquartered in Menlo Park, California. It connects accredited investors with Jan 6, 2023 12:43pm. With a strong M&A environment for exits, venture capitalists continue to fuel biotech industry growth. Asia Pacific ; All quotes delayed a minimum of 15 minutes. Founded in 2012, Social Starts is a set of early-stage venture funds that uses analytics to uncover and invest in the strongest companies in the strongest investment segments. Over $14 billion was invested in Biopharma startups globally in 2022, with 37 notable IPOs of VC-backed Biotech enterprises raising a total of $4.2 billion. It closed its second Xontogeny-focused fund in May, giving it another $515 million to invest in a dozen or more companies. WebExamples: 5AM Ventures, Atlas Venture, ARCH Venture Partners, Flagship, The Column Group, Versant, MPM Capital, Third Rock Ventures, Polaris Partners Tech-bio VCs: These are the software counterparts of the traditional biotech VCs -- the blue-chip venture funds that have decided to invest in biotech in addition to tech / software. WebWith a total of USD 9.2bn, the oncology sector received the highest funding volume, followed by central nervous system (USD 6.0bn) and infectious diseases (USD 2.2bn). The largest deal of 2021 was the transaction of Treeline Biosciences (USD 735m), while the most active investor was Alexandria Venture Investments with 51 investments in 2021. According to its website, the business has 36 IPOS and $3.2 billion under control. See: http://fortune.com/2014/10/02/exclusive-atlas-venture-is-splitting-up/ VC firms only invest in companies that have long-term growth potential of at least 10X their investment, and that already have considerable traction (very fast revenue The firm seeks to invest in the computer hardware, software, commercial services, and healthcare sectors. The Indian startup/ VC ecosystem will truly come of age WebMarket-leading rankings and editorial commentary - see the top law firms & lawyers for Private equity: venture/growth capital in France. The firm prefers to invest in companies from the software, blockchain, robotics, software-as-a-service, artificial intelligence, and machine learning sectors. Asia Pacific ; WebTop Venture Capital News, Member Posts, Venture Capital Daily Indices and more! Insights about top trending companies, startups, investments and M&A activities, notable investors of these companies, their management team, and recent Insider analyzed corporate filings to identify the venture-capital firms that shaped these biotechs and are positioned to build on their success in 2022. Biotech is just one piece of its portfolio Mubadala also invests in aerospace, renewable energy, real estate, and several other industries. Business Products and Services (B2B), Healthcare Technology Systems, Information Technology, Founder & Managing Partner Leonard Lenny Saizan Jr. The release is based on public data and may miss organnizations who are not currently releasing their data. At the end of September, Flagship had $17 billion in assets under management. It seeks to invest in the information technology sector. But it had holdings in nine biotech companies that went public this year, including Vor Biopharma, Omega Therapeutics, and Adagio Therapeutics. The Legal 500; Europe, Middle East & Africa . Essex Woodlands was established by the Essex Venture Fund. Early Stage VC, Later Stage VC, Seed Round. The firm specializes in investing in the early-stage firm. RA Capital led the companys $336 million Series C ahead of the companys August IPO, though the firm hadnt participated in the companys earlier funding rounds. US biotechs still led on investments, although Europe The trend of increased biotech venture capital continues in 2021 with the newly announced fund NFX Bio. Private biotech investing is a small piece of what Fidelity does. 10 Figure calculated based on adding the value of the new $450 million fund with the $3.5 billion previously disclosed by the firm. WebFive out of the ten businesses selected to present at the 2021 event went on to raise $50m - $150m each within 12 months of the event and one raising a $23m Series A (others planning to raise in the next 6 months). The firm seeks to invest in companies operating in the information technology and tech-enabled services. It is noteworthy that the company identifies various affiliate investment companies, or New River Management Funds, which are smaller corporate venture capital funds with a regional concentration. Largest investment: 17.9 million shares of Evotec worth $936 million at the time of its IPO, Total holding value of 2021 IPOs: $1.6 billion. Third-ranked Flagship Pioneering, for instance, was driven by just two IPOs in 2021. If investment continues at the current pace, 2022 could likely top 2020 for total funding. It's a great way to keep an eye on up-and-coming companies with To learn more about these VC firms and their 2021 investments take a look at their Crunchbase profiles: RA Capital Management OrbiMed Northpond Ventures Temasek Flagship Pioneering offers a distinctive business strategy that conceives, develops, finances, and expands first-in-category ventures to revolutionize sustainability and human health. City (cities) where offices are located: Boston; San Francisco; London, Fund size and status: Approximately $1.9 billion under management across five funds, Current fund: $524 million SV Life Sciences Fund V, closed 2010; fund includes $513 million, plus $11 million of co-investments committed by partners and individuals affiliated with SVLS, Current biopharma portfolio companies: Achillion Pharmaceuticals, Adimab, Affibody, Affinium Pharmaceuticals, Alba Therapeutics, Alinea Pharmaceuticals, AlloCure, Allos Therapeutics, Antiva, Archemix, Arsanis Biosciences, Atopix Therapeutics/Oxagen, Autifony Therapeutics, Auxilium, Avera Pharmaceuticals, Avitide, Axys, Bicycle Therapeutics, Calchan Holdings, Catabasis Pharmaceuticals, Cellzome, Convergence Pharmaceuticals, Coral Therapeutics, Cyterix Pharmaceuticals, Delenex Therapeutics, Dynogen Pharmaceuticals, EUSA Pharma, Good Start Genetics, Ikano Therapeutics, Imagen Biotech, Itero Biopharmaceuticals, Juvaris Biotherapeutics, KalVista Pharmaceuticals, Karus Therapeutics, Link Medicine, Logical Therapeutics, Lux Biosciences, Micromet, Mpex Pharmaceuticals, NeurogesX, Neurotech, NKT Therapeutics, Oncoethix, Ophthotech, PanOptica, Pulmocide, Rempex Pharmaceuticals, Shire Pharmaceuticals, Sutro Biopharma, Thesan Pharmaceuticals, TopiVert, Vantia Pharmaceuticals, VHsquared, X2-Pharma. Added to this, a new administration in the United States and its policy proposals, taxes, immigration, trade policy, and other issues that directly affect both VC investors and companies will all be on the table next year, PitchBook said in its 2021 U.S. venture capital outlook report. The capital total is a staggering 46% increase from its last set of funds, closed in May 2021 at $1.3 billion. Largest investment: 13.2 million shares of Lyell Immunopharma worth $225.8 million at the time of its IPO, Total holding value of 2021 IPOs: $400.2 million. Founded in 2018, Cathexis Ventures is a corporate venture arm of Cathexis Holdings headquartered in Houston, Texas. These were the top 10 VC deals in Mass. With $19 billion in assets under management, OrbiMed is set to be a leader next year as well. 3. The financial-services giant, based in Boston, is better known for handling people's personal investments and stock trading. Latest biotech merger sees aimless Adamis snapped up by DMK - FierceBiotech 4h ago Vivo is based in Palo Alto, California, but also has offices in Beijing, Shanghai, Hong Kong, and Taiwan. Following is a list of the top 15 venture capital firms in 2023. 3 The general partners of the Life Sciences team and Advanced Technology Ventures joined investors from both in 2012 to create a new firm, Lightstone Ventures. Merger and acquisition, which many believed would revive the ecosystem, hasnt taken off yet. Alta Partners. It has even created startups in-house over the past couple of years. The firm is headquartered in San Francisco, California. A total of 162 SPACs listed so far this year have raised $55 billion, an increase of 501.8% on capital raised and 295.1% in count from 2019. 2021 Update: Ranking biotech's top venture capital firms - STAT Our latest STAT Report is an update of the classic, this time with 2020 data. Cormorant Capital, a Boston-based investing group with $3 billion in assets under management, was founded in 2013 by Bihua Chen. Largest investment: 18.2 million shares of Adagio Therapeutics worth $46.9 million at the time of its IPO, Total holding value of 2021 IPOs: $468.7 million. The firm seeks to invest in the media, software, and healthcare sectors. Essex Woodlands Health Ventures, City (cities) where offices are located: Palo Alto, CA; Houston; New York; London; Shanghai, Fund size and status: More than $2.5 billion under management across eight funds (4), Current fund: $900 million Fund VIII, closed 2009 (4), Current biopharma portfolio companies: Acura Pharmaceuticals, Biotoscana, Bioventus, Catalyst Biosciences, Chroma Therapeutics, Corium, Curis, Echo Therapeutics, Elusys Therapeutics, Horizon Pharma, IntegenX, LightSciences Oncology, Medicinova, Molecular Partners, Open Monoclonal Technology, Oraya Therapeutics, Revance Therapeutics, Symphogen, Ziopharm Oncology, City (cities) where offices are located: Cambridge, MA; New York; Palo Alto, CA, Fund size and status: $2.6 billion under management across seven funds, Current funds: $450 million Venrock VII, closed July 2014 and intended to invest in technology and healthcare companies; $350 million Venrock VI, closed 2010 (5), Current biopharma portfolio companies: Acceleron Pharma, Achaogen, Anacor Pharmaceuticals, Ariosa Diagnostics, Avalanche Biotech, AVEO Pharmaceuticals, Celladon, Cerulean, Constellation Pharmaceuticals, CymaBay Therapeutics, Fate Therapeutics, Hua Medicine, Infinity Pharmaceuticals, Intarcia Therapeutics, Ironwood Pharma, Juno Therapeutics, QuatRx Pharmaceuticals, Receptos, Vitae Pharmaceuticals, City (cities) where offices are located: Boston (6); South San Francisco, CA; Gainesville, FL; Munich, Fund size and status: More than $2.6 billion committed capital under management across five funds, Current fund: Approximately $300 million MPM BioVentures V L.P., closed 2010 (7), Current biopharma portfolio companies: 23andMe, Amphivena Therapeutics, Anthera Pharmaceuticals, Aratana Therapeutics, Astute Medical, Celladon, Cerecor, Chiasma, Conatus Pharmaceuticals, Epizyme, Iconic Therapeutics, Mitokyne, Proteon Therapeutics, Radius Health, Rhythm Pharmaceuticals, SAI, Selexys Pharmaceuticals, Sideris Pharmaceuticals, Solasia Pharma, Syndax Pharmaceuticals, Theraclone Sciences, True North Therapeutics, Vascular Pharmaceuticals, Verastem, City (cities) where offices are located: Princeton, NJ, and San Diego, Fund size and status: More than $2.7 billion under management across eight funds, Current fund: $500 million Domain Partners VIII, closed 2009, Current biopharma portfolio companies: Achaogen, Achillion Pharmaceuticals, Adynxx, Afferent Pharmaceuticals, Aldeyra Therapeutics, Alimera Sciences, Applied Proteomics, Ariosa Diagnostics, Ascenta Therapeutics, Asmacure, Astute Medical, Atara Biotherapeutics, aTyr Pharma, BioNano Genomics, Cantex Pharmaceuticals, Celator Pharmaceuticals, Clovis Oncology, CoDa Therapeutics, CoLucid Pharmaceuticals, Dicerna Pharmaceuticals, Domain Elite Holdings, Domain Russia Investments, Eddingpharm International Holdings, Epic Sciences, Esperion Therapeutics, Evoke Pharma, Five Prime Therapeutics, IntegenX, Marinus Pharmaceuticals, Meritage Pharma, NovaDigm Therapeutics, Ocera Therapeutics, Oraya Therapeutics, Orexigen Therapeutics, Otonomy, ProteinSimple, Regardo Biosciences, Sera Prognostics, Syndax Pharmaceuticals, Tobira Therapeutics, Tragara Pharmaceuticals, VentiRx Pharmaceuticals, Veracyte, Zogenix, Fund size and status: $2.8 billion under management across 10 funds, Current fund: $650 million InterWest Partners X, closed 2008, Current biopharma portfolio companies: Applied Genetic Technologies (AGTC), Alvine Pharmaceuticals, Arcion Therapeutics, Carbylan Therapeutics, Cebix, Centrexion, Cidara Therapeutics, Drais Pharmaceuticals, Eiger BioPharmaceuticals, Lycera, MacroGenics, Ocera Therapeutics, On Demand Therapeutics, Paratek Pharmaceuticals, PMV Pharma, QuatRx Pharmaceuticals, RadioRx, Tesaro, Trius Therapeutics, USDS, Xenon Pharmaceuticals, City (cities) where offices are located: Cambridge, MA. See: http://www.sec.gov/Archives/edgar/data/1609495/000160949214000002/xslFormDX01/primary_doc.xml MPM BioVentures was approaching the end of fundraising, according to an unnamed market source, Reuters PE Hub reported on Sept. 18. That seventh fund closed $50 million higher than the $400 million offering amount that the firm stated back on June 17, when it disclosed its plan to raise the fund in a Form D filing with the U.S. Securities and Exchange Commission. WebThe 45 most important VCs in Texas, according to other VCs. Knowing a venture capital firms investment portfolio is crucial before contacting them. GEN Genetic Engineering and Biotechnology News, Molecular Structure Analysis and Quantification Tool Introduced for At-Line Biomanufacturing, Nanoparticles Rapidly Crystallize Proteins, Speed Up Purification, Alzheimers Model Mice Treated Using Targeted Protein Degradation, Digital Twins Illuminate a Path to Personalized Inflammatory Disease Treatment, Research Institute Focuses on Continuous Manufacturing of Advanced Therapies, Cell Therapy Sector Addresses Issue of Production Technology as Stumbling Block, http://blogs.wsj.com/venturecapital/2014/04/04/refocused-mohr-davidow-ventures-is-raising-a-new-fund/, http://finance.yahoo.com/news/lightstone-ventures-closes-first-fund-123257593.html, http://www.sec.gov/Archives/edgar/data/1612343/000161234314000001/xslFormDX01/primary_doc.xml, https://www.sec.gov/Archives/edgar/data/1602264/000160226414000001/xslFormDX01/primary_doc.xml, http://www.sec.gov/Archives/edgar/data/1609495/000160949214000002/xslFormDX01/primary_doc.xml, http://fortune.com/2014/10/02/exclusive-atlas-venture-is-splitting-up/, http://myemail.constantcontact.com/Announcing-Fund-VII.html?soid=1106633098844&aid=84wvr4fxTTs, http://www.sec.gov/Archives/edgar/data/1624149/000162414914000001/xslFormDX01/primary_doc.xml, http://www.sec.gov/Archives/edgar/data/1611731/000161173114000001/xslFormDX01/primary_doc.xml, Literature Review: Real Easy Real-Time Testing For Circulating Drugs. Founded in 1989, OrbiMed, an investing powerhouse based in New York, has shaped biotech for decades with its investments. The firm seeks to accelerate companies in the software, media and technology sectors in Texas. In 1999, Versant Ventures, Inc., a Menlo Park, California-based venture capital company, was founded. Insider analyzed more than 90 IPOs to find the top venture-capital firms that led biotech in 2021. Since Mubadala is a sovereign wealth fund, investing on behalf of the United Arab Emirates and the government of Abu Dhabi. Current biopharma portfolio companies: Hyperion Therapeutics, OpGen, City (cities) where offices are located: Menlo Park, CA; Westport, CT; New York; Gurgaon, India; Herzliya Pituach, Israel, Fund size and status: $4.2 billion under management across nine funds, Current fund: $675 million Canaan Partners X, announced Oct. 16, Current biopharma portfolio companies: Aldea Pharmaceuticals, Arvinas, Axial Exchange, Chimerix, Chrono Therapeutics, CytomX, Dermira, Durata Therapeutics, Envisia Therapeutics, LQ3 Pharma, Marinus Pharmaceuticals, Novira Therapeutics, Sample6, Semnur Pharmaceuticals, Spinifex Pharmaceuticals, Theraclone Sciences, Tobira Therapeutics, VaxInnate, City (cities) where offices are located: New York; San Francisco; Mumbai; Shanghai; Herzliya, Israel, Fund size and status: Approximately $12 billion under management in five public funds, as well as private equity funds in North America/Europe, Asia, and Israel; and a Royalty Opportunities Fund launched 2011 to invest in healthcare royalty streams, Current fund: $325 million OrbiMed Asia Partners II, closed September; $735 million OrbiMed Private Investments V, closed October 2013, Current biopharma portfolio companies: Acceleron Pharma, Adaptimmune, Aerocrine, Adimab, Aerpio, Affimed, Alector, Amarin, Ambit Biosciences, Anthera, arGEN-X, ARMO BioSciences, Arsanis Biosciences, Arteaus, Audentes Therapeutics, Avitide, Bharat Serums and Vaccines, Biodel, BioLineRx, Cardioxyl, cCAM Biotherapeutics, Cerenis Therapeutics, Cleave Biosciences, Clementia, Dimension Therapeutics, Durata Therapeutics, Eddingpharm, GC-Rise Pharmaceutical, Good Start Genetics, Igenica, Intercept Pharmaceuticals, Invitae, Iroko Pharmaceuticals, Loxo Oncology, Mirati Therapeutics, Otic Pharma, Otonomy, OxOnc Development, PharmAbcine, Pieris, Principia Biopharma, ProNAi, RDD Pharma, RedHill Biopharma, Relypsa, Response BioMedical, Roka BioScience, Sage Therapeutics, Selecta Biosciences, Shasun, singulex, Symbionics Therapeutics, Waterstone Pharmaceuticals, #2. Asia Pacific ; The Legal 500; United States . Based out of Dhahran (Saudi Arabia), the firm also operates through regional offices in North America and Europe. The ecosystem of Biotech ventures peaked in 2021. The firm seeks to make investments in companies operating in business software, consumer internet, cloud service, enterprise software and other technology sectors. 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